Description
Description: SEC13 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 342 amino acids (1-322 a.a.) and having a molecular mass of 37.7kDa. The SEC13 is purified by proprietary chromatographic techniques.
Introduction: SEC13 is a member of the SEC13 family of WD-repeat proteins. SEC13 is a constituent of the endoplasmic reticulum and the nuclear pore complex. SEC13 is similar to the yeast SEC13 protein that is essential for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. SEC13 interacts with SEC31A and SEC31B. SEC31A colocalizes with SEC13, one of the other components of COPII, in the subcellular structures corresponding to the vesicle transport function